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KMID : 1035620160040030221
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Allergy Asthma & Respiratory Disease
2016 Volume.4 No. 3 p.221 ~ p.224
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Toxic epidermal necrolysis induced by deflazacort
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Youn Da-Il
Kim Min-Hye
Koh Seok-Woong
Kim Jung-Won
Yoon Sang-Eun
Jeon Hyeon-Kyeong
Cho Young-Joo
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Abstract
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Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions to drugs, which carry significant morbidities and mortalities. Although SJS and TEN can be treated by corticosteroids or intravenous immunoglobulin, they may be induced by steroids. We experienced a 36-year-old man who developed whole body erythromatous maculopapular rashes and multiple bullae after ingestion of deflazacort. After avoidance of deflazacort and use of dexamethasone, skin lesions resorbed. We reported a case of TEN diagnosed by characteristic clinical findings with a brief review of the literature.
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KEYWORD
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Stevens-Johnson syndrome, Nephrotic syndrome, Drug hypersensitivity syndrome
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